Pamelor For Depression

According to the National Institute of Mental Health (NIMH), around 19.4 million adults in the United States, or 7.8% of the U.S. adult population, had at least one major depressive episode in 2019.1 With the help of medications like nortriptyline, or Pamelor, the chemical imbalance caused by depression may be be more readily treated.


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What is Pamelor?

You might be wondering, “What is nortriptyline or Pamelor?” The answer to this question is that Pamelor is commonly prescribed to patients suffering from mental health problems due to its efficacy to improve mood, relieve anxiety and tension, increase energy level, and boost feelings of wellbeing. Nortriptyline side effects may include dry mouth, blurred vision, and constipation.

The side effects are usually not severe and often fade when the body adjusts to the presence of the medication. It is important to look into Pamelor interactions to better understand if you are taking other medication that creates negative Pamelor interactions. Knowing the Pamelor drug class can help you with this.

Pamelor is the nortriptyline brand name. Nortriptyline is a tricyclic antidepressant that affects chemicals in the brain that may be unbalanced in people with depression. It is generally prescribed to treat symptoms of depression. It can also be used off-label to treat illnesses such as chronic pain, diabetic neuropathy, myofascial pain, orofacial pain, and postherpetic neuralgia.2

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Pamelor Generic Name and Brand Name

The Pamelor drug class, or Pamelor in general, is the brand name of an antidepressant drug called nortriptyline. Brand name Pamelor is available as a capsule and in liquid form. Generic nortriptyline is only available as a capsule.

What is Pamelor Used For?

Pamelor is prescribed to patients suffering from mental health problems, including depression, for its efficacy to improve mood, relieve anxiety and tension, increase energy level, and boost feelings of wellbeing. It affects the balance of certain neurotransmitters in the brain, such as norepinephrine and serotonin.

How Should I Take Pamelor?

Patients should always take the medication as directed by their doctor or pharmacist. Pamelor is available in two forms: as capsules and in liquid form. The medicine should be taken by mouth, 1 to 4 times per day. Patients using the liquid form should measure their doses carefully by using the special measuring spoon that comes with the Pamelor medication.

What is Depression?

Depression is a mental health disorder that causes feelings of sadness and loss of interest in things that normally bring fun and pleasure. Depression usually lasts for weeks or months and can interfere with daily life and relationships with friends and family.

There are several types of depression, including:

  • Major depressive disorder that affects more than 16.1 million American adults.3
  • Roughly 4.4% of U.S. adults experience bipolar disorder at some time in their lives.4
  • Around 2.5% of U.S. adults experience a persistent depressive disorder at some time in their lives.5

Causes of Depression

Depression has many different causes, including:

  • Brain chemistry: Brain chemistry is one of the factors that may increase the risk of depression. People who have depression have a chemical imbalance in parts of the brain that manage mood, thoughts, sleep, appetite, and behavior.
  • Genetics: Genetics plays a role in the development of depression. A person with a family member who has depression is more likely to develop it, and there is evidence that certain genes increase the risk of developing depression.
  • Life events: Certain life events can trigger depression, such as long-term unemployment, living in an abusive or uncaring relationship, long-term isolation or loneliness, prolonged work stress, etc.
  • Substance abuse issues: Alcohol and other addictive substances affect the chemistry of the brain, which increases the risk of depression.
  • Medical conditions: People suffering from life-threatening illnesses, such as coronary heart disease or cancer, are more prone to developing depression.

Signs and Symptoms of Depression

The signs and symptoms of depression can range from feelings of sadness to frequent thoughts of death. Here are some of the most common signs and symptoms:

  • Problems concentrating, thinking, or remembering things
  • Feelings of sadness or hopelessness
  • Anger issues, often over small matters
  • Anxiety, agitation, or restlessness
  • Mood swings
  • Sleeping too much or too little
  • Loss of interest in all normal activities, such as sex or hobbies
  • Lack of energy
  • Weight loss or weight gain
  • Feelings of worthlessness or guilt
  • Frequent thoughts of death, suicide thoughts, suicide attempts
  • Unexplained physical pain, such as back pain or headaches
Infographic - Celexa used for

Pamelor Dosage, Uses, and Withdrawal

Can Pamelor Help With Depression?

Pamelor is a tricyclic antidepressant that works by preventing the reabsorption of neurotransmitters called serotonin and norepinephrine.6 When there are not enough neurotransmitters in the brain, depression may appear. The restoration of these neurotransmitters in the brain can improve a depressive person’s mood, sleep, appetite, and energy levels.

Pamelor Dosage

Pamelor dosage is based on the patient’s age, medical condition, and response to therapy. Dosage should begin at a low level and be increased as required.

The general dosage for adults is anywhere from Pamelor 5 mg to Pamelor 10 mg, with intake levels of upwards of 25 mg in most cases. Pamelor generic name is often administered anywhere from three to four times per day on average. The maximum daily dose is 150 milligrams. The medication can be taken a few times per day or as a single dose before bedtime. The recommended dosage for elderly patients is 30 mg to 50 mg per day.

Withdrawal Symptoms

Abrupt discontinuation of Pamelor can cause a range of withdrawal symptoms according to Pamelor reviews. The most common withdrawal symptoms include the following:

  • Headache
  • Restlessness
  • Anxiety
  • Chills
  • Muscle pain
  • Dizziness
  • Nausea
  • Vomiting
  • Sweating

From Pamelor reviews left by people who have experience with the drug, in order to avoid experiencing withdrawal symptoms, your doctor may recommend reducing the dose gradually over several weeks.

Pamelor Side Effects

Short-Term Effects

Pamelor is a prescription medicine, and as such, it can have side effects. The most common side effect is drowsiness, which may be manageable with dose adjustments. Some other possible Pamelor side effects include these:

  • Dry mouth
  • Blurred vision
  • Constipation
  • Heartburn
  • Dizziness
  • Headache
  • Insomnia
  • Tachycardia
  • Impaired coordination
  • Increased appetite
  • Nausea
  • Confusion
  • Restlessness
  • Anxiety
  • Libido changes

If you are currently taking Pamelor, it is essential to be aware of these potential side effects and consult your doctor if you experience any issues.

Long-Term Effects

For most patients, Pamelor is safe to take for an extended period of time. The drug does not seem to produce any lasting side effects, even if the patient has been taking the drug for several months or years. However, Pamelor does produce withdrawal symptoms if discontinued abruptly. Patients who have been taking the medication for a long period and in higher doses are more likely to experience these withdrawal symptoms.

How Long Do Pamelor Side Effects Last?

The side effects of Pamelor tend to fade away once the body adjusts to the medicine. If you experience any side effects for a prolonged period, consult with your health care professional. They may gradually reduce your dose to minimize the negative side effects.

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Frequently Asked Questions About Nortriptyline (Pamelor)

What Happens If I Miss a Dose?

If you miss a dose, take it as soon as you can. Skip the missed dose if it is almost time for your next dose. Do not take the two doses at the same time.

What Should I Avoid While Taking Pamelor?

It is recommended to avoid drinking alcohol while taking Pamelor until you see how the medicine affects you. Avoid unprotected exposure to sunlight as Pamelor makes your skin more susceptible to sunburn. As this drug may make you dizzy, drowsy, or blur your vision, avoid driving or doing any other dangerous activity until you can do it safely.

What Happens If I Overdose on Nortriptyline?

The most common overdose symptoms of Pamelor include irregular heartbeats, severe drowsiness, vision problems, hallucinations, confusion, agitation, vomiting, stiff muscles, feeling hot or cold, seizures, or coma. If you think you or a loved one may have overdosed, call your doctor or the Poison Control center at (800) 222-1222. If your loved one is not breathing, call 911 immediately.


We also accept many others insurance plans. verify your benefits with no obligation required.


OR CALL US 24/7: (844) 926-0729


We also accept many others insurance plans. verify your benefits with no obligation required.


OR CALL US 24/7: (844) 926-0729